Umbilical Metastasis as Primary Manifestation of Cancer: A Small Series and Review of the Literature
Published: October 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.4997
Kyriakos Psarras, Nikolaos Symeonidis, Minas Baltatzis, Athanasios Notopoulos, Christina Nikolaidou
1. Second Propedeutical, Department of Surgery, Aristotle University of Thessaloniki, School of Health Sciences, Hippokratio General Hospital, Thessaloniki, Greece.
2. Second Propedeutical, Department of Surgery, Aristotle University of Thessaloniki, School of Health Sciences, Hippokratio General Hospital, Thessaloniki, Greece.
3. Second Propedeutical, Department of Surgery, Aristotle University of Thessaloniki, School of Health Sciences, Hippokratio General Hospital, Thessaloniki, Greece.
4. Faculty, Department of Nuclear Medicine, Hippokratio General Hospital, Thessaloniki, Greece.
5. Faculty, Department of Pathology, Hippokratio General Hospital, Thessaloniki, Greece.
Correspondence
Dr. Nikolaos Symeonidis,
49 Konstantinoupoleos str, Second Propedeutical Department of Surgery,
Hippokratio General Hospital, PC 54642, Thessaloniki, Greece.
Phone : +3023106945703331, E-mail : niksym@hotmail.com
Umbilical metastasis is a rare manifestation of intra-abdominal cancer. It appears either as the first sign of a primary malignancy or as metastatic site of an already diagnosed cancer, representing an ominous prognostic finding. We report three cases of umbilical metastasis as the first sign of an underlying malignancy. Hypotheses about pathophysiology of umbilical metastasis are based on the embryological origin of the umbilicus and its residual communication with systematic, portal and lymphatic circulation.
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